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Program Information

Justification for the Creation of a Gene Regulation Graduate Program
A. Provide a defined curriculum for graduate students interested in studying mechanisms of gene regulation at the fundamental level and in relation to specific biological pathways and diseases.
B. Formalize and integrate into a defined program the current activities of UCLA's gene regulation laboratories, including the monthly joint meeting, weekly journal club, and "Leaders in the Field" seminar series. These activities have been ongoing and highly successful for the past 12 years.

Application Procedure
A. Interested students should apply through the UCLA ACCESS admissions program. On the application form, applicants will have the option of checking a box indicating that Gene Regulation is one of their top three areas of interest.
B. Strong applicants will be invited to an interview at the UCLA campus during one of several interview weekends in January or February. During the interview weekends, applicants will have an opportunity to meet with faculty and senior students affiliated with the Gene Regulation Program. In particular, they will have the option of choosing to join the Program's faculty and students for a dinner, which is usually held at the home of an affiliated faculty member. During the interview weekend, applicants may also fully explore their interests in other fields and areas of interest.
C. Decisions to accept or reject an applicant are made by the ACCESS admissions committee, in consultation with members of the Gene Regulation Program, within one week of the interview.

First-Year Students (Procedures and Curriculum)
A. Students who enter graduate school through UCLA ACCESS will have the option of becoming affiliated with the Gene Regulation Program immediately. Alternatively, students can explore diverse interests during their first-year, and then choose to enter the Gene Regulation Program at the end of the year, if they choose an affiliated laboratory.
B. Entering students will be asked by the ACCESS office whether they would like their first-year faculty advisor to be affiliated with the Gene Regulation Program. Like all ACCESS advisors, the advisor from the Gene Regulation Program will assist the students in choosing courses and their three research rotations.

C. Like all first-year ACCESS students, students interested in the Gene Regulation Program will have an opportunity to perform research rotations in any laboratory affilitated with the ACCESS program. They will not be restricted to laboratories within the Gene Regulation Program.
D. The first-year course curriculum for students interested in the Gene Regulation Program will be focused, yet flexible, which will allow students to explore other interests. During the Fall and Winter quarters, the curriculum conforms to the typical ACCESS curriculum, including Biological Chemistry M253 in the Fall quarter, a cell biology lecture course in the Winter quarter, and a 2-unit M297 seminar course each quarter. During the Spring quarter, students will be encouraged to enroll in Mechanisms of Transcription (CM259), an outstanding lecture course coordinated by Dr. Albert Courey. Students will have the option of enrolling in the Gene Regulation Journal Club (BC251) during spring quarter instead of the traditional M297 seminar course that is required for other first-year ACCESS students. The students will attend the Journal Club throughout the quarter and will give a presentation during one of the weeks, which will fulfill their seminar course requirement for that quarter.

E. First-year students will be encouraged to attend and participate in the monthly Gene Regulation meeting, weekly journal club, and "Leaders in the Field" seminar series. Lunch and dinner are provided at the journal club and monthly meeting, respectively.
F. At the end of the first year, students who choose to join a laboratory affiliated with the Gene Regulation Program will have the option of formally joining the Gene Regulation Graduate Program or, alternatively, any other graduate program with which the laboratory is affiliated.

Subsequent Years
A. During one quarter of the second year, students must enroll in a two-unit seminar course (M298). They must also formally enroll in the Gene Regulation Journal Club (BC251) during one quarter of their second year, as this will form the basis for their written qualifying exam (see below). As a final requirement during the second year, students will be required to assemble three members of their thesis commitee and present a brief 20-minute presentation describing their proposed thesis project. Before this meeting, the student should provide the committee members with a brief written proposal (two single-spaced page), which in most instances will be the same proposal the students supplied with their training grant applications at the end of the first year.
B. Throughout their graduate education, students are encouraged to attend the weekly journal club and monthly Gene Regulation Meeting.
C. Like all students who enter UCLA through the ACCESS program, students affiliated with the Gene Regulation Program will serve as Teaching Assistants during one quarter in the second year and one quarter in their third year. A special effort will be made to assign the Program's students to courses that allow them to make use of their gene regulation knowledge.
D.
Students will be required to take written and oral qualifying exams. The written exam will consist of an original research proposal (three single-spaced pages) relating to one of the papers covered in the journal club during the quarter they were enrolled in the journal club. The proposal will be critiqued by the leader of the journal club, Mike Carey, and by two other Gene Regulation Faculty members. The oral qualifying exam will consist of a research proposal (approximately 15 double-spaced pages) on a topic that is unrelated to their thesis project. This exam must be completed by the end of the fall quarter of the student's third year, or by the end of the winter quarter if the student serves as a Teaching Assistant in the fall quarter.
E. An oral defense of the Ph.D. thesis will be required.

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